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Optimization of Gadodiamide Concentration for MR Arthrography at 3 T

Department of Radiology, University of California, San Francisco, 400 Parnassus Ave., A 367, Box 0628, San Francisco, CA 94143-0628.

OBJECTIVE. The purpose of our study was to determine the optimal concentration of a gadolinium-based contrast agent (gadodiamide) for direct MR arthrography at 3 T compared with 1.5 T in an in vitro study.

CONCLUSION. Optimized concentrations of gadolinium-based contrast agents for MR arthrography are similar at 3 and 1.5 T, although a slightly greater dilution may be useful at 3 T. Signal-to-noise ratio peak levels are significantly reduced by adding an iodinated contrast agent, relatively significantly more at 3 T than at 1.5 T.

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