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AJR 2005; 185:126-131
© American Roentgen Ray Society

Clinical Observations

Lung Cancer Screening Experience: A Retrospective Review of PET in 22 Non-Small Cell Lung Carcinomas Detected on Screening Chest CT in a High-Risk Population

Rebecca M. Lindell1, Thomas E. Hartman1, Stephen J. Swensen1, James R. Jett2, David E. Midthun2, Mark A. Nathan1 and Val J. Lowe1

1 Department of Radiology, Mayo Clinic, 200 First St. SW, Rochester, MN 55905.
2 Department of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN 55905.

OBJECTIVE. The objective of our study was to retrospectively review the PET results of non-small cell lung carcinomas detected on screening chest CT in a high-risk population.

CONCLUSION. PET findings were negative in 32% of the cases of non-small cell carcinomas that were detected on screening CT in a high-risk patient population. These tumors were small, low-grade, or both. The most common histology was bronchioloalveolar cell carcinoma. The role of PET in evaluating screening-detected indeterminate noldules in a high-risk population may be more limited than in a general population.


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