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DOI:10.2214/AJR.04.0968
AJR 2005; 185:1299-1306
© American Roentgen Ray Society

Clinical Observations

Radiofrequency Ablation in a Porcine Lung Model: Correlation Between CT and Histopathologic Findings

Akira Yamamoto1, Kenji Nakamura1, Toshiyuki Matsuoka1, Masami Toyoshima1, Tomohisa Okuma1, Yoshimasa Oyama1, Yoshihiro Ikura2, Makiko Ueda2 and Yuichi Inoue1

1 Department of Radiology, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan.
2 Department of Pathology, Osaka City University Graduate School of Medicine, Abeno-ku, Osaka 545-8585, Japan.

OBJECTIVE. The objective of our study was to investigate the time course changes of the ablated lesion after radiofrequency ablation in the porcine lung and the correlation between CT and histopathologic findings.

CONCLUSION. Ground-glass attenuation on CT led to overestimation of the size of necrotic lesions. The layered structural findings on CT were consistent with the histopathologic findings. Although CT findings reflect the histopathologic findings, attention should be paid to the dissociation of ablated lesions and high-density areas in clinical interpretation of CT images.




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