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DOI:10.2214/AJR.04.1516
AJR 2006; 186:510-515
© American Roentgen Ray Society

Clinical Observations

MDCT Appearance of Gastrointestinal Stromal Tumors After Therapy with Imatinib Mesylate

Dinuke R. Warakaulle1 and Fergus Gleeson1

1 Both authors: Department of Radiology, The Churchill Hospital, Old Road, Oxford, OX3 7LJ, United Kingdom.

OBJECTIVE. Our objective was to determine the MDCT appearance of gastrointestinal stromal tumors (GISTs) after treatment with imatinib mesylate.

CONCLUSION. Cystic changes within primary and metastatic GISTs seen on MDCT in patients after imatinib mesylate therapy are evidence of disease response. Calcification may also occur in lesions that respond to therapy.

Keywords: CT • gastrointestinal imaging • gastrointestinal stromal tumors • imatinib mesylate • oncologic imaging


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