HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Wysowski, D. K. Articles by Nourjah, P. Search for Related Content PubMed PubMed Citation Articles by Wysowski, D. K. Articles by Nourjah, P. Social Bookmarking                      What's this? Hotlight (NEW!) What's Hotlight?

Deaths Attributed to X-Ray Contrast Media on U.S. Death Certificates

¹ Both authors: Division of Drug Risk Evaluation, Food and Drug Administration, HFD-433, White Oak, Building 22, Room 3424, 10903 New Hampshire Ave., Silver Spring, MD 20993.

OBJECTIVE. The objectives of our study were to determine the number, rate, and types of deaths attributed to specific X-ray contrast media on the basis of U.S. death certificates and to attempt to assess the comparative safety of commonly used diagnostic X-ray contrast agents using death certificate information.

CONCLUSION. From 1999 through 2001, deaths attributed to the International Classification of Diseases (ICD) code for contrast media occurred at the rate of 1.1–1.2 per million contrast media packages distributed. An analysis of 1999 death certificates indicated that most deaths attributed to contrast media predictably were associated with renal failure or nephropathy and anaphylaxis or allergic reactions. Risk assessment of the comparative safety of classes or agents was limited by lack of specific contrast media names. Names of administered contrast agents should be recorded in patients' medical records and communicated to primary care physicians and certifiers of death in the event of serious sequelae after an identified recent radiologic procedure.

Keywords: anaphylaxis • contrast media • death certificate • drug reactions • imaging report • mortality • renal failure

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				M. Sendeski, A. Patzak, T. L. Pallone, C. Cao, A. E. Persson, and P. B. Persson Iodixanol, Constriction of Medullary Descending Vasa Recta, and Risk for Contrast Medium-induced Nephropathy Radiology, June 1, 2009; 251(3): 697 - 704. [Abstract] [Full Text] [PDF]

				R. A. Halvorsen Which Study When? Iodinated Contrast-enhanced CT Versus Gadolinium-enhanced MR Imaging Radiology, October 1, 2008; 249(1): 9 - 15. [Full Text] [PDF]

				E. Seeliger, B. Flemming, T. Wronski, M. Ladwig, K. Arakelyan, M. Godes, M. Mockel, and P. B. Persson Viscosity of Contrast Media Perturbs Renal Hemodynamics J. Am. Soc. Nephrol., November 1, 2007; 18(11): 2912 - 2920. [Abstract] [Full Text] [PDF]