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DOI:10.2214/AJR.04.1797
AJR 2006; 186:634-638
© American Roentgen Ray Society


Original Research

Improving Diagnostic Accuracy of MDCT Coronary Angiography in Patients with Mild Heart Rhythm Irregularities Using ECG Editing

Filippo Cademartiri1,2, Nico R. Mollet1,2, Giuseppe Runza1,3, Timo Baks1,2, Massimo Midiri3, Eugene P. McFadden2, Thomas G. Flohr4, Bernd Ohnesorge4, Pim J. de Feyter1,2 and Gabriel P. Krestin1

1 Department of Radiology, Erasmus Medical Center, Dr. Molewaterplein, 40, Rotterdam 3015GD, The Netherlands.
2 Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands.
3 DIBIMEL, Section of Radiological Sciences, University of Palermo, Palmero, Italy.
4 Computed Tomography, Siemens Medical Solutions, Forchheim, Germany.

OBJECTIVE. The objective of our study was to compare diagnostic accuracy of MDCT coronary angiography in a population of patients with mild heart rhythm irregularities before and after editing the ECG.

SUBJECTS AND METHODS. Thirty-eight patients who underwent MDCT coronary angiography and conventional coronary angiography were enrolled in the study. The inclusion criterion was the presence of mild heart rhythm irregularities (i.e., premature beats; atrial fibrillation; mistriggering; or low heart rate, defined as 40 beats per minute or less) during the scan. All patients underwent MDCT with the following parameters: 16 detectors; collimation, 0.75 mm; gantry rotation time, 375 msec; 120 kV; and effective milliampere-second setting, 500–600. Images were reconstructed in two settings: before ECG editing and after ECG editing (i.e., arbitrary modification of temporal windows within the cardiac cycle at the site of mild heart rhythm irregularities). Data sets were scored for the presence of significant stenoses (≥ 50% lumen reduction) in coronary segments ≥ 2 mm diameter. The results of the two groups were compared with a McNemar test, and a p value of less than 0.05 was considered significant.

RESULTS. The sensitivity, specificity, and negative and positive predictive values of MDCT coronary angiography for the detection of significant stenoses before and after ECG editing were 63% (41/65) and 92% (78/85); 97% (251/260) and 96% (305/317); 87% (62/71) and 87% (81/93); 91% (251/275) and 97% (305/313), respectively (p < 0.05). The proportion of nonassessable segments was reduced from 17% (70/416) before ECG editing to 2% (10/416) after.

CONCLUSION. ECG editing significantly improves diagnostic accuracy in a selected population of patients with mild heart rate irregularities.

Keywords: arteriography • coronary angiography • ECG editing • heart rhythm • MDCT angiography


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