HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Figures Only Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Chang, J. S. Articles by Lee, V. S. Search for Related Content PubMed PubMed Citation Articles by Chang, J. S. Articles by Lee, V. S. Social Bookmarking                      What's this? Hotlight (NEW!) What's Hotlight?

Opposed-Phase MRI for Fat Quantification in Fat-Water Phantoms with ¹H MR Spectroscopy to Resolve Ambiguity of Fat or Water Dominance

¹ Westwood Radiology Associates, Pascack Valley Hospital, Westwood, NY 07675.
² Department of Radiology, NYU Medical Center, 560 First Ave., TCH-HW 202, New York, NY 10016.
³ Siemens Medical Solutions, Malvern, PA 19355.
⁴ Department of Radiology, Robert Wood Johnson University Hospital, East Brunswick, NJ 08816.

OBJECTIVE. The purpose of the study was to quantify the fat fraction in nine fat-water phantoms containing 0-80% fat using opposed-phase imaging with the qualitative guidance of ¹H MR spectroscopy (MRS), which was used by observer 1 to visually assess the sizes of the water and fat peaks to apply two alternative mathematic formulas for the calculation of the fat fraction. In addition, the fat fraction was also quantified directly with ¹H MRS as an independent method by two observers (observers 2 and 3).

CONCLUSION. The fat fraction calculated with opposed-phase imaging (FF_OPI) and that calculated with ¹H MRS (FF_MRS) correlated well with the known fat fractions of the phantoms (FF_P): r = 0.99 for FF_OPI; p < 0.0001 and r = 0.96-0.98 for FF_MRS; p < 0.001, for observers 2 and 3, respectively. Opposed-phase imaging should be combined with ¹H MRS to ensure accurate quantification of the fat fraction.

Keywords: liver disease • MRI • SPECT

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				N. Pineda, P. Sharma, Q. Xu, X. Hu, M. Vos, and D. R. Martin Measurement of Hepatic Lipid: High-Speed T2-Corrected Multiecho Acquisition at 1H MR Spectroscopy--A Rapid and Accurate Technique Radiology, August 1, 2009; 252(2): 568 - 576. [Abstract] [Full Text] [PDF]

				F. H. Cassidy, T. Yokoo, L. Aganovic, R. F. Hanna, M. Bydder, M. S. Middleton, G. Hamilton, A. D. Chavez, J. B. Schwimmer, and C. B. Sirlin Fatty Liver Disease: MR Imaging Techniques for the Detection and Quantification of Liver Steatosis1 RadioGraphics, January 1, 2009; 29(1): 231 - 260. [Abstract] [Full Text] [PDF]

				D. P. O'Regan, M. F. Callaghan, M. Wylezinska-Arridge, J. Fitzpatrick, R. P. Naoumova, J. V. Hajnal, and S. A. Schmitz Liver Fat Content and T2*: Simultaneous Measurement by Using Breath-hold Multiecho MR Imaging at 3.0 T--Feasibility Radiology, May 1, 2008; 247(2): 550 - 557. [Abstract] [Full Text] [PDF]