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DOI:10.2214/AJR.05.0317
AJR 2006; 187:W198-W201
© American Roentgen Ray Society

Clinical Observations

Acute Generalized Exanthematous Pustulosis as a Delayed Dermatotoxic Reaction to IV-Administered Nonionic Contrast Media

Aaron Peterson1, Richard W. Katzberg1, Maxwell A. Fung2,3, Sandra L. Wootton-Gorges1 and William Dager4

1 Department of Radiology, University of California Davis Medical Center, 4860 Y St., Ste. 3100, Sacramento, CA 95817.
2 Department of Dermatology, University of California Davis Medical Center, Sacramento, CA.
3 Department of Pathology, University of California Davis Medical Center, Sacramento, CA.
4 Department of Pharmacology, University of California Davis Medical Center, Sacramento, CA.

OBJECTIVE. Our objective was to report three delayed, generalized, and protracted cutaneous reactions in two patients that are compatible with acute generalized exanthematous pustulosis (AGEP) after contrast medium administration.

CONCLUSION. Radiologists and referring clinicians need to be aware of late adverse reactions to the administration of contrast media and to distinguish these from other possible causes.

Keywords: contrast media • CT


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A. A. Hammerbeck, N. H. Daniels, and J. P. Callen
Ioversol-Induced Acute Generalized Exanthematous Pustulosis: A Case Report
Arch Dermatol, June 1, 2009; 145(6): 683 - 687.
[Abstract] [Full Text] [PDF]


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