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DOI:10.2214/AJR.05.1068
AJR 2006; 187:W399-W405
© American Roentgen Ray Society


Clinical Observations

Liver Involvement in Hereditary Hemorrhagic Telangiectasia: CT and Clinical Findings Do Not Correlate in Symptomatic Patients

Jim S. Wu1,2, Sanjay Saluja1, Guadalupe Garcia-Tsao3, Alice Chong1, Katherine J. Henderson1 and Robert I. White, Jr.1

1 Department of Diagnostic Radiology, Yale University School of Medicine and Yale-New Haven Hospital, New Haven, CT.
2 Present address: Department of Radiology, Beth Israel Deaconness Medical Center, 330 Brookline Ave., Landry Bldg., Rm. 357, Boston, MA 02215.
3 Department of Gastroenterology, Section of Digestive Diseases, Yale University School of Medicine and Yale-New Haven Hospital, New Haven, CT.

OBJECTIVE. The purpose of our study was to report the multiphasic CT findings in patients with symptomatic liver involvement by hereditary hemorrhagic telangiectasia (HHT) and to correlate the CT findings with the type of clinical presentation.

CONCLUSION. Patients with symptomatic HHT liver disease have diffuse hepatic telangiectases, a dilated common hepatic artery, and a high incidence of biliary abnormalities. Multiphasic CT is useful in diagnosing liver involvement due to HHT; however, no strong correlation was seen between CT findings and the clinical subtype of HHT liver disease.

Keywords: congenital malformations • CT • hepatobiliary imaging • hereditary hemorrhagic telangiectasia • liver disease


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