| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Original Research |
1 Department of Radiology, Massachusetts General Hospital, FND 202, 55 Fruit
St., Boston, MA 02114.
2 Present address: Department of Radiology, University of Cincinnati Medical
Center, Cincinnati, OH.
3 Institute for Technology Assessment, Massachusetts General Hospital, Boston,
MA.
OBJECTIVE. The objective of this study was to determine the optimal breathing protocol for combined PET/CT scans of the thorax.
SUBJECTS AND METHODS. Eighty combined PET/CT scans were obtained in 64 patients (30 women, 34 men; mean age, 57 years; range, 19-86 years). The 80 PET/CT scans consisted of five group of patients (16 PET/CT scans per group) who underwent whole-body combined 18F-FDG PET/CT with different CT breathing protocols: expiration, mid suspended breath-hold, quiet breathing, small breath in, and regular breath in. The quality of alignment was analyzed at the diaphragm, aortic arch, heart, thoracic spine, and lung apices using a scale of ratings from 1 (very poor) to 5 (excellent). The Kruskal-Wallis test was used to compare alignment between breathing protocols for each anatomic reference point.
RESULTS. Alignment of the PET and CT data sets was excellent with three breathing protocols: expiration, mid suspended breath-hold, and quiet breathing, with no statistical differences. Significant misalignment occurred at the diaphragm (p < 0.0001) and heart (p < 0.0001) with the small breath-in and regular breath-in techniques.
CONCLUSION. Excellent image fusion of combined PET/CT data sets in the thorax, especially at the diaphragm and heart, can be achieved with expiration, mid suspended breath-hold, or quiet breathing. Quiet breathing is recommended for optimal patient comfort during acquisition of attenuation-correction CT data sets.
Keywords: computer-assisted • image analysis • CT • image reconstruction • positron emission • PET/CT
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
This article has been cited by other articles:
|
|
 |
|
  S. Kligerman and S. Digumarthy Staging of Non-Small Cell Lung Cancer Using Integrated PET/CT Am. J. Roentgenol., November 1, 2009; 193(5): 1203 - 1211. [Full Text] [PDF]
|
|
|
|
 |
|
 W. De Wever, S. Stroobants, J. Coolen, and J. A. Verschakelen Integrated PET/CT in the staging of nonsmall cell lung cancer: technical aspects and clinical integration Eur. Respir. J., January 1, 2009; 33(1): 201 - 212. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. J. Slomka, L. Le Meunier, S. W. Hayes, W. Acampa, M. Oba, G. G. Haemer, D. S. Berman, and G. Germano Comparison of Myocardial Perfusion 82Rb PET Performed with CT- and Transmission CT-Based Attenuation Correction J. Nucl. Med., December 1, 2008; 49(12): 1992 - 1998. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Kawano, E. Ohtake, and T. Inoue Deep-Inspiration Breath-Hold PET/CT of Lung Cancer: Maximum Standardized Uptake Value Analysis of 108 Patients J. Nucl. Med., August 1, 2008; 49(8): 1223 - 1231. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. L. Gould, T. Pan, C. Loghin, N. P. Johnson, and S. Sdringola Reducing Radiation Dose in Rest-Stress Cardiac PET/CT by Single Poststress Cine CT for Attenuation Correction: Quantitative Validation J. Nucl. Med., May 1, 2008; 49(5): 738 - 745. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. L. Gould, T. Pan, C. Loghin, N. P. Johnson, A. Guha, and S. Sdringola Frequent Diagnostic Errors in Cardiac PET/CT Due to Misregistration of CT Attenuation and Emission PET Images: A Definitive Analysis of Causes, Consequences, and Corrections J. Nucl. Med., July 1, 2007; 48(7): 1112 - 1121. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
