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Primary Pulmonary Hypertension: 3D Dynamic Perfusion MRI for Quantitative Analysis of Regional Pulmonary Perfusion

¹ Department of Radiology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.
² Department of Radiology, Beth Israel Deaconess Medical Center, Boston, MA 02215.
³ Department of Medical Engineering, Division of Allied Health Sciences, Osaka University Medical School, Osaka, Japan.

OBJECTIVE. The purpose of this study was to determine whether quantitative pulmonary perfusion parameters obtained from 3D dynamic contrast-enhanced MR perfusion data can be used to assess the severity of primary pulmonary hypertension (PPH) as indicated by pulmonary vascular resistance (PVR) and mean pulmonary artery pressure (MPAP).

CONCLUSION. Three-dimensional dynamic contrast-enhanced MRI has potential for assessment of disease severity as indicated by PVR and MPAP in patients with PPH.

Keywords: chest • lung • MRI • perfusion • pulmonary hypertension

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