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DOI:10.2214/AJR.05.2131
AJR 2007; 188:57-68
© American Roentgen Ray Society

Perspective

Solitary Pulmonary Nodules: Detection, Characterization, and Guidance for Further Diagnostic Workup and Treatment

Yeong Joo Jeong1,2, Chin A. Yi1 and Kyung Soo Lee1

1 Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50, Ilwon-dong, Kangnam-gu, Seoul 135-710, South Korea.
2 Present address: Department of Diagnostic Radiology, Pusan National University Hospital, Pusan National University School of Medicine and Medical Research Institute, Pusan, Korea.

Abstract

OBJECTIVE. The purpose of our study is to improve radiologists' understanding of the clinical issues involved in making a diagnosis and to guide further diagnostic workup and treatment of solitary pulmonary nodules (SPNs).

CONCLUSION. Information on the morphologic and hemodynamic characteristics of SPNs provided by dynamic helical CT, with high specificity and reasonably high accuracy, can be used for initial assessment. PET/CT is more sensitive at detecting malignancy than dynamic helical CT, and all malignant nodules may be potentially diagnosed as malignant by both techniques. Therefore, PET/CT may be selectively performed to characterize SPNs that show indeterminate results at dynamic helical CT.

Keywords: chest imaging • dynamic CT • lung • lung neoplasms • PET/CT • screening • solitary pulmonary nodules


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