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Microwave Ablation of Renal Parenchymal Tumors Before Nephrectomy: Phase I Study

¹ Department of Urology and Comprehensive Cancer Center of Wake Forest University, Winston-Salem, NC.
² Present address: Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, TN.
³ Department of Pathology, Wake Forest University Health Sciences, Winston-Salem, NC.
⁴ Department of Radiology, Wake Forest University Health Sciences, Medical Center Blvd., Winston-Salem, NC 27157.
⁵ Present address: Piedmont Urological Associates, High Point, NC.

OBJECTIVE. The purpose of this study was to determine, in renal neoplasms, the size of ablation zones induced in vivo with percutaneous microwave probes and whether skip areas remain within the ablation zones.

CONCLUSION. For a single 10-minute ablation, ablated volumes averaged 27 cm³ and 105 cm³ with a single-probe and a three-probe ablation array, respectively. There were no skip areas within the ablated zone. Microwave ablation can safely and quickly generate large ablation lesions and renal neoplasms.

Keywords: interventional radiology • kidney • microwave coagulation therapy • oncology • percutaneous ablation

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