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DOI:10.2214/AJR.05.1998
AJR 2007; 188:W459-W463
© American Roentgen Ray Society

Clinical Observations

Focal Nodular Hyperplasia-Like Nodules in Alcoholic Liver Cirrhosis: Radiologic-Pathologic Correlation

Young Han Lee1, Seong Hyun Kim1,2, Mee-Yon Cho3, Kwang Yong Shim4 and Myung Soon Kim1

1 Department of Radiology, Wonju Christian Hospital, Wonju College of Medicine, Yonsei University, 162 Ilsan-dong, Wonju, Gangwon-do 220-701, South Korea.
2 Present address: Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Gangnam-gu, Seoul 135-710, South Korea.
3 Department of Pathology, Wonju Christian Hospital, Wonju College of Medicine, Yonsei University, Wonju, Gangwon-do 220-701, South Korea.
4 Department of Oncology, Wonju Christian Hospital, Wonju College of Medicine, Yonsei University, Wonju, Gangwon-do 220-701, South Korea.

OBJECTIVE. The purpose of this study was to describe our experience with three patients who had pathologically proven focal nodular hyperplasia (FNH)-like nodules that radiologically mimicked hepatocellular carcinoma (HCC).

CONCLUSION. FNH-like nodules may radiologically mimic HCC, appearing as hypervascular masses on contrast-enhanced CT images and as high-signal-intensity masses on superparamagnetic iron oxide-enhanced MR images. Pathologically, there is the presence of a high number of unpaired arteries and sinusoidal capillarization, which may mimic HCC. Thus, it is important to differentiate FNH-like nodules radiologically, pathologically, and clinically from HCC.

Keywords: cirrhosis • focal nodular hyperplasia • hepatocellular carcinoma • liver disease


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