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DOI:10.2214/AJR.06.0245
AJR 2007; 188:1589-1595
© American Roentgen Ray Society

Clinical Observations

Imaging Findings of Leukemic Involvement of the Pancreaticobiliary System in Adults

Eugene K. Choi1,2, Jae Ho Byun1, Soon Jin Lee3, Seung Eun Jung4, Mi-Suk Park5, Seong Ho Park1 and Moon-Gyu Lee1

1 Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 388-1 Pungnap-2dong, Songpa-gu, Seoul 138-736, Korea.
2 Weill Medical College of Cornell University, New York, NY.
3 Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
4 Department of Radiology, St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
5 Department of Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

OBJECTIVE. Our objective was to review the imaging findings of patients with leukemic involvement of the pancreaticobiliary system in adults.

CONCLUSION. Pancreatic myeloid and lymphoid leukemia show single or multiple mass lesions of homogeneous low attenuation and poor contrast enhancement on CT that is radiographically indistinguishable from that of pancreatic lymphoma. Although more cases are needed for confirmation, leukemic infiltration of the biliary tract is characterized by wall thickening of the bile duct with minimal contrast enhancement—a feature that may be helpful in differentiating it from infiltrating hilar or extrahepatic cholangiocarcinoma.

Keywords: biliary system • CT • pancreas • pancreatic neoplasms • pancreaticobiliary imaging


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