| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Original Research |
1 Department of Radiology, University College Hospital, Newcastle Rd., Galway,
Ireland.
2 Department of Oncology, University College Hospital, Galway, Ireland.
OBJECTIVE. The purpose of our study was to determine the prevalence of unsuspected venous thromboembolic disease—specifically, of pulmonary embolism (PE) and of inferior vena cava (IVC), iliac, and iliofemoral deep venous thromboses (DVTs)—in oncology patients on staging CT scans of the thorax, abdomen, and pelvis.
MATERIALS AND METHODS. Retrospective analysis was performed on 435 consecutive staging CT thorax, abdomen, and pelvis scans performed on a variety of oncology patients for the presence of venous thromboembolic disease. The patient group consisted of 198 men and 237 women who ranged in age from 20 to 79 years (mean, 55 years). Disease type, stage, concomitant surgery or chemoradiation therapy regimes, anticoagulation status, and 6-month clinical and radiologic follow-up findings were recorded.
RESULTS. We found a prevalence of 6.8% (23/339) unsuspected iliofemoral, 1.2% (4/339) unsuspected common iliac, and 0.3% (1/315) unsuspected IVC DVTs and 3.3% (13/397) unsuspected PEs occurring in patients with a wide range of malignancies. The overall prevalence of unsuspected venous thromboembolism (i.e., DVT, PE, or both) was 6.3% (25/397). DVT, PE, and venous thromboembolic disease were more common in inpatients (p = 0.002, 0.004, 0.023; relative risk [RR] = 1.6, 2.1, 1.4, respectively) and in those with advanced disease (p = 0.001, 0.01, 0.001; RR = 2.2, 1.8, 2.0, respectively).
CONCLUSION. Although there is a known increased risk of thromboembolism (DVT and PE) in oncology patients, many cases are not diagnosed, which can prove fatal. Staging CT simultaneously affords one sole investigation of the pulmonary, IVC, iliac, and upper femoral veins, thereby providing an important diagnostic opportunity. Assessment for DVT and PE is important when reviewing staging CT scans.
Keywords: cancer staging • CT staging • deep venous thrombosis • oncologic imaging • pulmonary embolism • thromboembolic disease • venous thromboembolism
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
This article has been cited by other articles:
|
|
 |
|
  J. Kodama, N. Seki, S. Masahiro, T. Kusumoto, K. Nakamura, A. Hongo, and Y. Hiramatsu D-dimer level as a risk factor for postoperative venous thromboembolism in Japanese women with gynecologic cancer Ann. Onc., February 3, 2010; (2010): mdq012v1 - mdq012. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 V. Sopov, H. Bernstine, D. Stern, N. Yefremov, J. Sosna, and D. Groshar The Metabolic Spectrum of Venous Thrombotic Disorders Found on PET/CT Am. J. Roentgenol., December 1, 2009; 193(6): W530 - W539. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Vormittag, R. Simanek, C. Ay, D. Dunkler, P. Quehenberger, C. Marosi, C. Zielinski, and I. Pabinger High Factor VIII Levels Independently Predict Venous Thromboembolism in Cancer Patients: The Cancer and Thrombosis Study Arterioscler Thromb Vasc Biol, December 1, 2009; 29(12): 2176 - 2181. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. B. Streiff Diagnosis and Initial Treatment of Venous Thromboembolism in Patients With Cancer J. Clin. Oncol., October 10, 2009; 27(29): 4889 - 4894. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Bierry, N. Holl, F. Kellner, S. Riehm, M.-N. Roedlich, M. Greget, and F. Veillon Venous Thromboembolism and Occult Malignancy: Simultaneous Detection During Pulmonary CT Angiography with CT Venography Am. J. Roentgenol., September 1, 2008; 191(3): 885 - 889. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
