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MRI Findings of Giant Cell Tumors of the Spine

¹ Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea.
² Present address: Department of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 388-1, Pungnap-2 dong, Songpa-ku, Seoul 138-736, Korea.
³ Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
⁴ Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul, Korea.

OBJECTIVE. The purpose of this article is to describe the MRI features of giant cell tumors of the spine in 10 patients.

CONCLUSION. One of the tumors was located in C7. The other nine tumors were located in the thoracic spine, lumbar spine, and sacrum, three in each site. The characteristic findings included an expansile mass with heterogeneous low to intermediate signal intensity on the T2-weighted images (10/10), a curvilinear area of signal void on T1- and T2-weighted images (9/10), and cystic changes within the mass (4/10). Although no imaging feature was pathognomonic, MRI was found to be valuable in identifying the tumor, revealing its extent, and defining its relationship with the intraspinal structures.

Keywords: giant cell tumors • MRI • musculoskeletal imaging • spine

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