HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Figures Only Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Poplack, S. P. Articles by Nagy, H. M. Search for Related Content PubMed PubMed Citation Articles by Poplack, S. P. Articles by Nagy, H. M. Social Bookmarking                      What's this?

Digital Breast Tomosynthesis: Initial Experience in 98 Women with Abnormal Digital Screening Mammography

¹ Department of Radiology, Dartmouth-Hitchcock Medical Center, One Medical Center Dr., Lebanon, NH 03756.
² Department of Community and Family Medicine, Dartmouth Medical School, Hanover, NH.
³ Norris Cotton Cancer Center, Lebanon, NH.

OBJECTIVE. The purpose of our study was to compare the image quality of tomosynthesis with that of conventional mammography and to estimate the recall rate of screening when tomosynthesis is used in addition to mammography.

MATERIALS AND METHODS. Women with an abnormal screening mammography were recruited sequentially. Consenting women underwent tomosynthesis of the affected breast corresponding to the views obtained with diagnostic mammography. The study radiologist compared the image quality, including lesion conspicuity and feature analysis, of tomosynthesis with diagnostic film-screen mammography and assessed the need for recall when tomosynthesis was added to digital screening mammography. Screening recalls were considered unnecessary when tomosynthesis did not show a corresponding abnormality or allowed definitely benign lesion characterization. Fisher's exact test was used to determine the association of equivalence and recall status with mammographic finding type.

RESULTS. There were 99 digital screening recalls in 98 women. The image quality of tomosynthesis was equivalent (n = 51) or superior (n = 37) to diagnostic mammography in 89% (88/99). Finding type was significantly (p < 0.001) associated with equivalence. Approximately half—52/99 (52%)—of the findings would not have been recalled when digital screening mammography was supplemented with tomosynthesis. When adjusting for confounding conditions, the recall reduction was 40% (37/92). The likelihood of recall was also dependent on finding type (p = 0.004).

CONCLUSION. Subjectively, tomosynthesis has comparable or superior image quality to that of film-screen mammography in the diagnostic setting, and it has the potential to decrease the recall rate when used adjunctively with digital screening mammography.

Keywords: breast • breast cancer • digital mammography • screening • tomosynthesis

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				W. F. Good, G. S. Abrams, V. J. Catullo, D. M. Chough, M. A. Ganott, C. M. Hakim, and D. Gur Digital Breast Tomosynthesis: A Pilot Observer Study Am. J. Roentgenol., April 1, 2008; 190(4): 865 - 869. [Abstract] [Full Text] [PDF]

				D. Gur Tomosynthesis: Potential Clinical Role in Breast Imaging Am. J. Roentgenol., September 1, 2007; 189(3): 614 - 615. [Full Text] [PDF]