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Dedicated Cone-Beam Breast CT: Feasibility Study with Surgical Mastectomy Specimens

¹ Department of Diagnostic Radiology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Unit 1350, Houston, TX 77030.
² Department of Imaging Physics, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030.
³ Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030.

OBJECTIVE. The purpose of this study was to investigate the feasibility of diagnostic breast imaging using a flat-panel detector-based cone-beam CT system.

CONCLUSION. Imaging of 12 mastectomy specimens was performed at 50–80 kVp with a voxel size of 145 or 290 µm. Our study shows that cone-beam breast CT images have exceptional tissue contrast and can potentially reduce examination time with comparable radiation dose.

Keywords: breast neoplasm • CT radiography • mastectomy • radiation dose • specimen radiography

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