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DOI:10.2214/AJR.07.2389
AJR 2007; 189:1397-1401
© American Roentgen Ray Society

Clinical Observations

Necrotizing Granuloma of the Lung: Imaging Characteristics and Imaging-Guided Diagnosis

Rennae Thiessen1, Jean M. Seely1, Frederick R. K. Matzinger1, Prachi Agarwal1,2, Karen L. Burns3, Carole J. Dennie1 and Rebecca Peterson1

1 Department of Diagnostic Imaging, The Ottawa Hospital, 1053 Carling Ave., Ottawa, ON K1Y 4E9, Canada.
2 Present address: Department of Radiology, University of Michigan Medical Center, Ann Arbor, MI.
3 Department of Pathology, The Ottawa Hospital, Ottawa, ON, Canada.

OBJECTIVE. The purpose of this study was to assess CT findings and the sensitivities of imaging-guided fine-needle aspiration (FNA) biopsy and core needle biopsy in the diagnosis of necrotizing granuloma of the lung.

CONCLUSIONS. The CT characteristics of necrotizing granuloma are indistinguishable from those of malignant tumors; tissue diagnosis therefore is necessary. Core needle biopsy is a sensitive method for diagnosing necrotizing granuloma of the lung, but FNA biopsy is insufficient for diagnosis.

Keywords: CT-guided biopsy • lung biopsy • necrotizing granuloma • pulmonary nodule • solitary pulmonary nodule


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