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DOI:10.2214/AJR.07.2225
AJR 2007; 189:W375-W381
© American Roentgen Ray Society


Clinical Observations

Imaging Appearance of Intrathecal Catheter Tip Granulomas: Report of Three Cases and Review of the Literature

Jinnah A. Phillips1, Edward J. Escott2, John J. Moossy3 and Harry C. Kellermier4

1 Department of Radiology, University of Pittsburgh Medical Center, UPMC Presbyterian, 200 Lothrop St., Pittsburgh, PA 15213.
2 Division of Neuroradiology, Department of Radiology, University of Pittsburgh Medical Center, UPMC Presbyterian, Pittsburgh, PA.
3 Department of Neurological Surgery, University of Pittsburgh Medical Center, UPMC Presbyterian, Pittsburgh, PA.
4 Division of Neuropathology, Department of Pathology, University of Pittsburgh Medical Center, UPMC Presbyterian, Pittsburgh, PA.

OBJECTIVE. The purpose of this article is to discuss the clinical, radiologic, and pathologic features of intrathecal catheter tip inflammatory masses and to review the literature regarding this phenomenon.

CONCLUSION. Formation of inflammatory masses at catheter tips can complicate chronic intrathecal opioid administration and have devastating neurologic sequelae. It is critical that radiologists recognize this entity and prompt immediate neurosurgical evaluation.

Keywords: catheter tip • complications • granuloma • inflammatory mass • intrathecal • opioid


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