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DOI:10.2214/AJR.07.7011
AJR 2008; 190:S23-S28
© American Roentgen Ray Society

Methodology and Application of Clinical Trials in Radiology: Self-Assessment Module

William C. Black1, Elizabeth A. Krupinski2, Annemarie Relyea-Chew3 and Felix S. Chew3

1 Department of Radiology, Dartmouth-Hitchcock Medical Center, Lebanon, NH.
2 Department of Radiology Research, University of Arizona, Tucson, AZ.
3 Department of Radiology, University of Washington, Box 354755, 4245 Roosevelt Way NE, Seattle, WA 98105.

The educational objectives of this self-assessment module are for the participant to understand the differences between cohort and case-control studies in radiology, to understand the advantages of randomized controlled trials over observational studies, to understand the basic principles underlying the use of imaging examinations for screening asymptomatic populations for particular diseases, and to understand the biases associated with the use of survival statistics in the evaluation of screening.

Keywords: clinical trials methodology • radiology research study design • screening by imaging


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