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Contrast Volume Reduction with Superior Vena Cava Catheter-Directed Coronary CT Angiography: Comparison with Peripheral IV Contrast Enhancement in a Swine Model

¹ Department of Diagnostic Radiology, William Beaumont Hospital, 3601 W 13 Mile Rd., Royal Oak, MI 48073.
² Division of Cardiovascular Disease, William Beaumont Hospital, Royal Oak, MI.
³ Research Institute-Biostatistics, William Beaumont Hospital, Royal Oak, MI.

OBJECTIVE. Conventional MDCT angiography uses a traditional peripheral IV approach for contrast injection; however, we describe our experience with a superior vena cava (SVC) catheter approach for coronary artery MDCT angiography as a potential means of decreasing iodinated contrast volume.

CONCLUSION. Central SVC contrast injection can decrease the contrast volume by 50% while maintaining coronary attenuation similar to that of peripheral IV injection. This approach has potential in reducing the contrast volume on coronary MDCT angiography studies and therefore the risk of contrast-induced nephropathy in certain high-risk patients. Further studies with higher injection rates and faster scan acquisition are needed for defining a lower contrast volume threshold.

Keywords: catheter angiography • coronary artery angiography • CT angiography • reduced contrast burden • superior vena cava approach