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DOI:10.2214/AJR.07.3488
AJR 2008; 191:1122-1128
© American Roentgen Ray Society

Clinical Observations

Solitary Necrotic Nodules of the Liver: Cross-Sectional Imaging Findings and Follow-Up in Nine Patients

Stefano Colagrande1, Maria Lara Paolucci1, Luca Messerini2, Wolfgang Schima3, Alfred Stadler3, Tommaso Vincenzo Bartolotta4, Angelo Vanzulli5 and Giuseppe Brancatelli4,6

1 Department of Clinical Physiopathology, Section of Radiodiagnostics, University of Florence, Viale Morgagni 85, Azienda Ospedaliero-Universitaria Careggi, 50134 Florence, Italy.
2 Department of Human Pathology and Oncology, University of Florence, Florence, Italy.
3 Department of Radiology, Medical University of Vienna, Vienna, Austria.
4 Department of Radiology, University of Palermo, Palermo, Italy.
5 Department of Diagnostic and Interventional Radiology, Niguarda Ca Granda Hospital, Milan, Italy.
6 Department of Radiology, University of Pittsburgh School of Medicine, Pittsburgh, PA.

OBJECTIVE. The purpose of our study was to retrospectively evaluate the sonographic, CT, and MRI findings (number, diameter, lobar location, depth from the hepatic capsule, and appearance of lesions) in a series of nine patients with pathologically proven solitary necrotic nodules of the liver and the natural evolution at follow-up in four of the nine patients.

CONCLUSION. Solitary necrotic nodules are usually small, solitary lesions, mainly located under the liver capsule of the right lobe. They are hypoechoic on sonography, hypoattenuating on CT, have low signal intensity on both T1- and T2-weighted MRI with lack of enhancement after IV contrast administration, and at follow-up have a tendency to show calcification and involution toward reduction in size.

Keywords: liver metastases • liver neoplasm • solitary necrotic nodules


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