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DOI:10.2214/AJR.08.1038.1
AJR 2008; 191:1129-1139
© American Roentgen Ray Society


Review

MRI Safety Update 2008: Part 1, MRI Contrast Agents and Nephrogenic Systemic Fibrosis

Frank G. Shellock1 and Alberto Spinazzi2

1 Keck School of Medicine, University of Southern California and Institute for Magnetic Resonance Safety, Education, and Research, 7511 McConnell Ave., Los Angeles, CA 90045.
2 Group Medical and Regulatory Affairs, Bracco Diagnostics, Inc., Princeton, NJ.

OBJECTIVE. This article is the first part of a two-part series on MRI safety. In this article, part 1, the topic of MRI contrast agents and nephrogenic systemic fibrosis (NSF) is addressed.

CONCLUSION. To prevent incidents and accidents associated with MRI, it is necessary to regularly revisit the safety topics that directly impact patient management especially with respect to the subjects that are "new" (e.g., MRI contrast agents and NSF), those that should be reassessed because of recent changes, topics that deserve emphasis because of controversy or confusion, and information that should be considered in light of new findings.

Keywords: 3-T MRI • devices • gadolinium-based contrast agents • implants • MRI artifacts • MRI contrast agents • MRI safety • nephrogenic systemic fibrosis


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