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DOI:10.2214/AJR.07.4027
AJR 2009; 192:450-454
© American Roentgen Ray Society

Clinical Observations

Characterization of Adrenal Pheochromocytoma Using Respiratory-Triggered Proton MR Spectroscopy: Initial Experience

Sooah Kim1, Nouha Salibi2, Andrew D. Hardie1,3, Jian Xu2, Ruth P. Lim1, Vivian S. Lee1 and Bachir Taouli1

1 Department of Radiology, New York University Langone Medical Center, 530 First Ave., MRI, New York, NY 10016.
2 Siemens Medical Solutions USA, Malvern, PA.
3 Present address: Department of Radiology, Medical University of South Carolina, Charleston, SC.

OBJECTIVE. The aim of our study was to evaluate the feasibility of respiratory-triggered proton single-voxel MR spectroscopy for the diagnosis of adrenal pheochromocytoma and to determine whether certain spectral resonances detected on single-voxel MR spectroscopy are specific for adrenal pheochromocytomas compared with adrenal adenomas.

CONCLUSION. Adrenal pheochromocytomas have a unique MR spectral signature, showing 6.8 ppm resonance that is not seen in adenomas. This unique spectral signature may be attributed to the presence of catecholamines and catecholamine metabolites that are abundant in pheochromocytomas.

Keywords: adenoma • adrenal gland neoplasms • catecholamine • MR spectroscopy • pheochromocytoma


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