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DOI:10.2214/AJR.08.2246
AJR 2009; 192:1190-1196
© American Roentgen Ray Society


Review

Language Networks in Children: Evidence from Functional MRI Studies

Jennifer Vannest1, Prasanna R. Karunanayaka1, Vincent J. Schmithorst1, Jerzy P. Szaflarski2 and Scott K. Holland1

1 Pediatric Neuroimaging Research Consortium, Cincinnati Children's Hospital Research Foundation and Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave., ML 5033, Cincinnati, OH 45229-5033.
2 Department of Neurology, The Neuroscience Institute and Center for Imaging Research, University of Cincinnati Academic Health Center, Cincinnati, OH.

OBJECTIVE. The purpose of our study was to review functional MRI and other neuroimaging studies of language skills in children from infancy to adulthood.

CONCLUSION. Functional MRI (fMRI) and other neuroimaging studies show developmental changes in the networks of brain regions supporting language, which can be affected by brain injuries or neurologic disorders. Particular aspects of language rely on networks that lateralize to the dominant hemisphere; others rely on bilateral or nondominant mechanisms. Multiple fMRI tasks for pediatric patients characterize functional brain reorganization that may accompany language deficits.

Keywords: brain development • child language • functional MRI • language development • pediatric neuroimaging


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