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DOI:10.2214/AJR.08.2304
AJR 2009; 192:1209-1218
© American Roentgen Ray Society

Review

Evidence-Based Outcomes of Studies Addressing Diagnostic Accuracy of MRI of Juvenile Idiopathic Arthritis

Elka Miller1,2, Elizabeth Uleryk1 and Andrea S. Doria1

1 Department of Radiology, Hospital for Sick Children and University of Toronto, Toronto, ON, Canada.
2 Present address: Department of Diagnostic Imaging, McMaster University Medical Centre, Hamilton Health Sciences, MUMC Site, 1200 Main St. W, Hamilton, ON L&N 3Z5, Canada.

OBJECTIVE. Our objective was to semiquantitatively evaluate the diagnostic accuracy of MRI for evaluation of synovium and cartilage of peripheral joints in juvenile idiopathic arthritis (JIA) according to the levels of evidence and recommendations of the Canadian Task Force on Periodic Health Examination guidelines.

CONCLUSION. Articles were screened using MEDLINE, EMBASE, DARE, and the Cochrane Library. Two independent reviewers assessed whether the currently available MRI techniques are accurate for diagnosis of synovial hypertrophy and cartilage degeneration in children with JIA. Overall, there is fair (grade B) strength of evidence that MRI is an accurate diagnostic method for evaluating synovium and cartilage and for assessing clinical responsiveness to treatment in peripheral joints in JIA.

Keywords: children • evidence-based medicine • juvenile idiopathic arthritis • MRI


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