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Imaging Localized Prostate Cancer: Current Approaches and New Developments

¹ Molecular Imaging Program, National Cancer Institute, National Institutes of Health, 10 Center Dr., MSC 1182, Bldg. 10, Rm. 1B40, Bethesda, MD 20892-1088.
² Biometric Research Branch, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD.

OBJECTIVE. Prostate cancer is the most common noncutaneous malignancy among men in the Western world. Imaging has recently become more important in the diagnosis, local staging, and treatment follow-up of prostate cancer. In this article, we review conventional and functional imaging methods as well as targeted imaging approaches with novel tracers used in the diagnosis and staging of prostate cancer.

CONCLUSION. Although prostate cancer is the second leading cause of cancer death in men, imaging of localized prostate cancer remains limited. Recent developments in imaging technologies, particularly MRI and PET, may lead to significant improvements in lesion detection and staging.

Keywords: MRI • PET • prostate cancer

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