HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Figures Only Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Google Scholar Articles by Siddiki, H. A. Articles by Mandrekar, J. N. PubMed PubMed Citation Articles by Siddiki, H. A. Articles by Mandrekar, J. N. Social Bookmarking                      What's this? Hotlight (NEW!) What's Hotlight?

Prospective Comparison of State-of-the-Art MR Enterography and CT Enterography in Small-Bowel Crohn's Disease

¹ Department of Radiology, Mayo Clinic, 200 First St., SW, Rochester, MN 55905.
² Miles and Shirley Fiterman Center for Digestive Diseases, Mayo Clinic, Rochester, MN.
³ Division of Biostatistics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN.

OBJECTIVE. The objective of our study was to prospectively obtain pilot data on the accuracy of MR enterography for detecting small-bowel Crohn's disease compared with CT enterography and with a clinical reference standard based on imaging, clinical information, and ileocolonoscopy.

SUBJECTS AND METHODS. The study group for this blinded prospective study was composed of 33 patients with suspected active Crohn's ileal inflammation who were scheduled for clinical CT enterography and ileocolonoscopy and had consented to also undergo MR enterography. The MR enterography and CT enterography examinations were each interpreted by two radiologists with disagreements resolved by consensus. The reports from ileocolonoscopy with or without mucosal biopsy were interpreted by a gastroenterologist. The reference standard for the presence of small-bowel Crohn's disease was based on the final clinical diagnosis by the referring gastroenterologist after reviewing all of the available information.

RESULTS. All 33 patients underwent CT enterography and ileocolonoscopy, 30 of whom also underwent MR enterography. The sensitivities of MR enterography and CT enterography for detecting active small-bowel Crohn's disease were similar (90.5% vs 95.2%, respectively; p = 0.32). The image quality scores for MR enterography examinations were significantly lower than those for CT enterography (p = 0.005). MR enterography and CT enterography identified eight cases (24%) with a final diagnosis of active small-bowel inflammation in which the ileal mucosa appeared normal at ileocolonoscopy. Furthermore, enterography provided the only available imaging in three additional patients who did not have ileal intubation.

CONCLUSION. MR enterography and CT enterography have similar sensitivities for detecting active small-bowel inflammation, but image quality across the study cohort was better with CT. Cross-sectional enterography provides complementary information to ileocolonoscopy.

Keywords: Crohn's disease • CT enterography • inflammatory bowel disease • MR enterography • small bowel

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				J. L. Fidler, L. Guimaraes, and D. M. Einstein MR Imaging of the Small Bowel RadioGraphics, October 1, 2009; 29(6): 1811 - 1825. [Abstract] [Full Text] [PDF]