HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Figures Only Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Google Scholar Articles by Dinter, D. J. Articles by Michaely, H. J. PubMed PubMed Citation Articles by Dinter, D. J. Articles by Michaely, H. J. Social Bookmarking                      What's this? Hotlight (NEW!) What's Hotlight?

Peripheral Bolus-Chase MR Angiography: Analysis of Risk Factors for Nondiagnostic Image Quality of the Calf Vessels—A Combined Retrospective and Prospective Study

¹ Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty of Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.
² Department of Radiology, Catholic Hospital, Koblenz, Germany.
³ Department of Medical Statistics, Biomathematics, and Information Technology, Medical Faculty of Mannheim, University of Heidelberg, Heidelberg, Germany.

OBJECTIVE. The objective of our study was to evaluate the influence of endogenous and exogenous risk factors on the rate of nondiagnostic examinations of the calves in peripheral bolus-chase MR angiography (MRA).

SUBJECTS AND METHODS. Peripheral bolus-chase MRA runoff studies in 177 patients with peripheral arterial occlusive disease (PAOD) were retrospectively assessed with regard to the rate of nondiagnostic image quality due to substantial venous overlay in the calf arteries requiring repeated MRA examinations. Logistic regression was used to analyze the rate of nondiagnostic MRA examinations as a function of several endogenous and exogenous risk factors and of the stage of PAOD. To probe the retrospective data, 22 consecutive patients were prospectively included and underwent a standard peripheral MRA examination if the probability of a nondiagnostic examination was less than 50% based on the results of logistic regression; otherwise, a hybrid MRA examination was ordered.

RESULTS. Nondiagnostic image quality of the calf arteries was found in 53 patients (30%). The incidence increased with each stage of PAOD up to 39% for stage IV. For each increase in the stage of PAOD, the probability of nondiagnostic image quality increased by a factor of 1.5561 (p = 0.0024). With an increasing number of risk factors, a significantly (p = 0.0074) higher rate of nondiagnostic images was found.

CONCLUSION. Based on the retrospective statistical analysis of PAOD stages and risk factors, selected patients can be triaged to undergo a specific hybrid MRA technique and thus circumvent the occurrence of nondiagnostic images and the need for repeated MRA examinations.

Keywords: MR angiography • peripheral arterial occlusive disease • peripheral vessels • runoff study • second injection • venous overlay

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?