HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH SEARCH RESULT		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Figures Only Full Text Full Text (PDF) A correction has been published Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Google Scholar Articles by Hara, A. K. Articles by Pavlicek, W. PubMed PubMed Citation Articles by Hara, A. K. Articles by Pavlicek, W. Social Bookmarking                      What's this? Hotlight (NEW!) What's Hotlight?

Iterative Reconstruction Technique for Reducing Body Radiation Dose at CT: Feasibility Study

¹ All authors: Department of Diagnostic Radiology, Mayo Clinic Arizona, 13400 E Shea Blvd., Scottsdale, AZ 85259.

OBJECTIVE. The purpose of this study was to evaluate the image noise, low-contrast resolution, image quality, and spatial resolution of adaptive statistical iterative reconstruction in low-dose body CT.

MATERIALS AND METHODS. Adaptive statistical iterative reconstruction was used to scan the American College of Radiology phantom at the American College of Radiology reference value and at one-half that value (12.5 mGy). Test objects in low- and high-contrast and uniformity modules were evaluated. Low-dose CT with adaptive statistical iterative reconstruction was then tested on 12 patients (seven men, five women; average age, 67.5 years) who had previously undergone routine-dose CT. Two radiologists blinded to scanning technique evaluated images of the same patients obtained with routine-dose CT and low-dose CT with and without adaptive statistical iterative reconstruction. Image noise, low-contrast resolution, image quality, and spatial resolution were graded on a scale of 1 (best) to 4 (worst). Quantitative noise measurements were made on clinical images.

RESULTS. In the phantom, low- and high-contrast and uniformity assessments showed no significant difference between routine-dose imaging and low-dose CT with adaptive statistical iterative reconstruction. In patients, low-dose CT with adaptive statistical iterative reconstruction was associated with CT dose index reductions of 32–65% compared with routine imaging and had the least noise both quantitatively and qualitatively (p < 0.05). Low-dose CT with adaptive statistical iterative reconstruction and routine-dose CT had identical results for low-contrast resolution and nearly identical results for overall image quality (grade 2.1–2.2). Spatial resolution was better with routine-dose CT (p = 0.004).

CONCLUSION. These preliminary results support body CT dose index reductions of 32–65% when adaptive statistical iterative reconstruction is used. Studies with larger statistical samples are needed to confirm these findings.

Keywords: body CT • low-dose CT • radiation dose

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				M. Wintermark and M.H. Lev FDA Investigates the Safety of Brain Perfusion CT AJNR Am. J. Neuroradiol., January 1, 2010; 31(1): 2 - 3. [Full Text] [PDF]

				A. C. Silva, H. J. Lawder, A. Hara, J. Kujak, and W. Pavlicek Innovations in CT Dose Reduction Strategy: Application of the Adaptive Statistical Iterative Reconstruction Algorithm Am. J. Roentgenol., January 1, 2010; 194(1): 191 - 199. [Abstract] [Full Text] [PDF]

				A. K. Hara, F. B. Walker, A. C. Silva, and J. A. Leighton Preliminary Estimate of Triphasic CT Enterography Performance in Hemodynamically Stable Patients With Suspected Gastrointestinal Bleeding Am. J. Roentgenol., November 1, 2009; 193(5): 1252 - 1260. [Abstract] [Full Text] [PDF]