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Radiological Reasoning: Bone Marrow Changes on MRI

¹ Department of Radiology, Mayo Clinic, 5777 E Mayo Blvd., Phoenix, AZ 85054.

OBJECTIVE

Differentiating neoplastic from nonneoplastic bone marrow changes on imaging can be challenging. MRI provides the most helpful information when using T1-weighted and opposed-phase (chemical shift) sequences. We discuss the MRI assessment of bone marrow in the context of a complex clinical case.

CONCLUSION

The case shows a false-positive result of opposed-phase imaging of bone marrow, which was a postinflammatory cause resulting in marrow fibrosis that mimicked neoplastic marrow infiltration and necessitated biopsy for definitive diagnosis.

Keywords: bone marrow • chemical shift imaging • fibrosis • MRI • neoplasm • opposed-phase imaging • red marrow reconversion

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Related articles in AJR:

Bone Marrow Changes on MRI: Self-Assessment Module

Catherine C. Roberts, William B. Morrison, Laura W. Bancroft, and Felix S. Chew
AJR 2009 193: S5-S9. [Abstract] [Full Text]  

This article has been cited by other articles:

				C. C. Roberts, W. B. Morrison, L. W. Bancroft, and F. S. Chew Bone Marrow Changes on MRI: Self-Assessment Module Am. J. Roentgenol., September 1, 2009; 193(3_Supplement): S5 - S9. [Abstract] [Full Text] [PDF]