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DOI:10.2214/AJR.08.2113
AJR 2009; 193:1228-1235
© American Roentgen Ray Society

Pictorial Essay

CT-Guided Core Biopsy of Lung Lesions: A Primer

I-Chen Tsai1,2, Wei-Lin Tsai1,2, Min-Chi Chen1,3, Gee-Chen Chang4,5,6, Wen-Sheng Tzeng3,7,8, Si-Wa Chan1 and Clayton Chi-Chang Chen1,3,9,10

1 Department of Radiology, Taichung Veterans General Hospital, Taichung, Taiwan.
2 Institute of Clinical Medicine, National Yang Ming University, Taichung, Taiwan.
3 Department of Radiological Technology and Graduate Institute of Radiological Science, Central Taiwan University of Science and Technology, Taichung, Taiwan.
4 Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.
5 School of Medicine, China Medical University, Taichung, Taiwan.
6 Institute of Biomedical Sciences, National Chung-Hsing University, Taichung, Taiwan.
7 Department of Medical Imaging, Chi-Mei Foundation Medical Center, No. 901, Chung Hwa Rd., Yong Kang City, Tainan 710, Taiwan.
8 Department of Radiology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
9 Department of Physical Therapy, Hungkuang University of Technology, Taichung, Taiwan.
10 Department of Physical Therapy and Assistive Technology, National Yang Ming University, Taipei, Taiwan.

OBJECTIVE. CT-guided core biopsy is playing an increasing role in the diagnosis of benign disease, cellular differentiation, somatic mutation analysis, and molecular fingerprint analysis.

CONCLUSION. In this article, we summarize the basic concepts, protocols, and techniques that we use for CT-guided core biopsy of lung lesions to assist radiologists in obtaining diagnostic specimens while reducing preventable complications.

Keywords: biopsy • CT • lung • lung cancer


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