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DOI:10.2214/AJR.08.2256
AJR 2009; 193:W411-W415
© American Roentgen Ray Society

Original Research

T2 Measurements of Cartilage in Osteoarthritis Patients With Meniscal Tears

Klaus M. Friedrich1, Timothy Shepard1, Valesca Sarkis de Oliveira2, Ligong Wang1, James S. Babb1, Mark Schweitzer3 and Ravinder Regatte1

1 Center for Biomedical Imaging, Department of Radiology, New York University, Langone Medical Center, 660 First Ave., New York, NY 10016.
2 Department of Radiology, Hospital Beneficencia Portuguesa de Sao Paulo, Sao Paulo, Brazil.
3 Department of Diagnostic Imaging, The Ottawa Hospital, Ottawa, ON, Canada.

OBJECTIVE. The objective of this study was to quantitatively assess cartilage degeneration via T2 mapping to compare patients with and those without meniscal tears.

SUBJECTS AND METHODS. Thirty-seven patients (18 men, mean age ± SD, 65.7 ± 7.8 years; 19 women, mean age, 63.8 ± 12.0 years) with clinical symptoms of osteoarthritis were studied on 3-T MRI using a 2D multiecho spin-echo sequence for T2 mapping. Meniscal signal and morphology were qualitatively graded and correlated to the T2 values of cartilage. Analysis of covariance, Bonferroni multiple comparison correction, and Spearman's correlation coefficients were used for statistical analysis.

RESULTS. Patients with meniscal tears (median ± interquartile range, 50.1 ± 6.1 milliseconds) had significantly (p = 0.021) higher T2 values of cartilage than those without meniscal tears (45.7 ± 4.8 milliseconds). T2 values of cartilage were significantly higher in the medial compartment than in the lateral compartment in patients with medial meniscal tears (p = 0.018).

CONCLUSION. T2 measurements are increased in patients with meniscal tears; this finding adds support to the theory of an association of osteoarthritis with damage to both the menisci and hyaline cartilage.

Keywords: cartilage • meniscal tears • MRI • osteoarthritis • T2 mapping


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