AJR InPractice
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Gharib, A. M.
Right arrow Articles by Freeman, A. F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Gharib, A. M.
Right arrow Articles by Freeman, A. F.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
Hotlight (NEW!)
Right arrow
What's Hotlight?
DOI:10.2214/AJR.09.2623
AJR 2009; 193:W478-W481
© American Roentgen Ray Society

Clinical Observations

Coronary Abnormalities in Hyper-IgE Recurrent Infection Syndrome: Depiction at Coronary MDCT Angiography

Ahmed M. Gharib1, Roderic I. Pettigrew2, Abdalla Elagha1, Amy Hsu3, Pam Welch4, Steven M. Holland3 and Alexandra F. Freeman3

1 Department of Radiology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Clinical Research Center, Bldg. 10, Rm. 3-5340, MSC 1263, 10 Center Dr., Bethesda, MD 20892.
2 National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD.
3 National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.
4 SAIC-Frederick, National Cancer Institute-Frederick, Frederick, MD.

OBJECTIVE. Hyper-IgE recurrent infection syndrome (HIES or Job's syndrome) is a rare disorder affecting the immune system and connective tissues. The purpose of this study is to describe the coronary abnormalities in genetically confirmed HIES patients as depicted by coronary MDCT angiography (MDCTA).

CONCLUSION. Coronary MDCTA has provided an opportunity for noninvasive evaluation of the coronary arteries in patients with HIES. These coronary abnormalities vary from tortuosity to ectatic dilation and focal aneurysms of the coronary arteries. Such an evaluation has potential value in identifying new aspects of this disease and thereby providing better understanding of the pathophysiology of the disorder.

Keywords: coronary abnormalities • coronary aneurysms • ectatic coronaries • hyper-IgE recurrent infection syndrome (HIES or Job's syndrome) • coronary MDCT angiography


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2009 by the American Roentgen Ray Society.