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Advances in Sonographic Detection of Ovarian Cancer: Depiction of Tumor Neovascularity With Microbubbles

¹ Department of Radiology and Imaging Sciences, Vanderbilt University Medical Center, 1161 21st Ave. S, Nashville, TN 37232-2675.
² Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, TN.
³ School of Medicine, Vanderbilt University Medical Center, Nashville, TN. School of Medicine, Vanderbilt University Medical Center, Nashville, TN.
⁴ Department of Obstetrics and Gynecology, Mt. Sinai School of Medicine, New York, NY.

OBJECTIVE. The purpose of this article is to discuss and illustrate the use of contrast-enhanced transvaginal sonography for the early detection of ovarian cancer and suggest how this technique may best be used to distinguish benign from malignant ovarian masses.

CONCLUSION. Microbubble-enhanced transvaginal sonography can enhance the evaluation of ovarian masses by early detection of tumor microvascularity.

Keywords: contrast-enhanced sonography • microbubble • ovarian cancer • sonography • tumor response • vasculature

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