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DOI:10.2214/AJR.09.3264
AJR 2010; 194:W141-W149
© American Roentgen Ray Society

Pictorial Essay

Imaging Findings in Immunosuppressed Patients With Epstein Barr Virus–Related B Cell Malignant Lymphoma

Alexander Sauter1, Christoph Faul2, Michael Bitzer3, Roland Bares4, Sabina Kraus2, Michael Fenchel1 and Marius Horger1

1 Department of Diagnostic and Interventional Radiology, Eberhard-Karls-University, Hoppe-Seyler-Str. 3, 72076 Tuebingen, Germany.
2 Department of Internal Medicine, South West German Cancer Center, Eberhard-Karls-University, Tuebingen, Germany.
3 Department of Gastroenterology and Hepatology, Medical University Hospital, Eberhard-Karls-University, Tuebingen, Germany.
4 Department of Nuclear Medicine, Medical University Hospital, Eberhard-Karls-University, Tuebingen, Germany.

OBJECTIVE. The purpose of this study was to describe multimodality imaging findings in immunosuppressed patients with Epstein-Barr virus (EBV)–related malignant lymphoproliferative diseases.

CONCLUSION. EBV-related malignant lymphoproliferative diseases share common features with other aggressive lymphomas, including a high degree of extranodal involvement, tumor vascularization, and tumor necrosis. Cognizance of the particular underlying diseases and conditions associated with the development of EBV-related lymphoproliferative diseases and associated imaging results should provide more accurate diagnosis.

Keywords: cross-sectional imaging • EBV-related lymphoma • Epstein-Barr virus (EBV) • FDG PET imaging • lymphoproliferative disease (LPD)


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