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American Journal of Roentgenology, Vol 96, 147-149, Copyright © 1966 by American Roentgen Ray Society

MODIFICATION OF RADIATION RESPONSE OF TUMORS BY ACTINOMYCIN D

CLINICAL EVALUATION

KLAUS RANNIGER M.D.1 and MELVIN L. GRIEM M.D.1

1 From the Department of Radiology, The University of Chicago, and the Argonne Cancer Research Hospital (operated by the University of Chicago for the United States Atomic Energy Commission), Chicago, Illinois

Experiments on laboratory animals show that variation of the time interval between actinomycin D injection and administration of ionizing radiation modifies the radiation response of cells. Clinical studies suggest that certain radioresistant tumors, especially certain sarcomas, may exhibit enhanced radiosensitivity under similar conditions.


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Copyright © 1966 by the American Roentgen Ray Society.