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1 From the Department of Radiology (Radiation Therapy Division) University of California, Center for the Health Sciences, Los Angeles, California
2 From the Department of Surgery (Urology), University of California, Center for the Health Sciences, Los Angeles, California
Excellent palliation and even cure are possible in some patients with Wilms' tumors even though both kidneys may be involved.
If the patients survive more than 2 years after termination of therapy without recurrence or persistence of disease, the chances for permanent cure are excellent.
The incidence of involvement of both kidneys may be as high as 5 to 10 per cent. The supposedly "normal" kidney should be examined at the time of surgery in spite of normal diagnostic studies in order to rule out bilateral involvement.
When patients with bilateral Wilms' tumors are treated, the possibility of producing radiation nephritis must be kept in mind.
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