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American Journal of Roentgenology, Vol 96, 664-676, Copyright © 1966 by American Roentgen Ray Society


VALIDITY OF MEASURING REGIONAL PULMONARY ARTERIAL BLOOD FLOW WITH MACROAGGREGATES OF HUMAN SERUM ALBUMIN

DONALD E. TOW 1, HENRY N. WAGNER JR. 1, VINCENT LOPEZ-MAJANO 1, EDWARD M. SMITH 1, and TOHRU MIGITA 1

1 From the Departments of Medicine and Radiology, The Johns Hopkins Medical Institutions, the Veterans Administration Hospital, Baltimore, Maryland and the Hospital for Special Surgery affiliated with the New York Hospital, Cornell Medical College, Department of Radiology

Evidence for the validity of the MAA method in the determination of regional pulmonary arterial blood flow is: (a) sizes of the particles are optimal; (b) extraction efficiency is high; (c) uniform mixing of the particles is complete prior to their arrival at the lungs; (d) the distribution of the macroaggregates and the red blood cells is similar; (e) correlation with differential spirometry in man at rest and during exercise is good; and (f) the known effects of erect posture and phasic variation of the respirators' cycle on the pattern of distribution of pulmonary blood flow in man were clearly demonstrated.


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