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American Journal of Roentgenology, Vol 96, 727-730, Copyright © 1966 by American Roentgen Ray Society


COMPUTER GENERATION OF NORMAL VALUES FOR THYROID I131 UPTAKES

ROBERT G. HOFFMANN Ph.D.1 and CLYDE M. WILLIAMS M.D., Ph.D.2

1 University of Miami Branch, Coral Gables, Florida; Formerly Research Assistant Professor, J. Hillis Miller Health Center, University of Florida, Gainesville, Florida
2 From the University of Florida Computing Center and from the Department of Radiology, University of Florida College of Medicine, Gainesville, Florida

A computer program written in Fortran for the IBM-709 has been described which performs the following operations on un-selected consecutive tests: (1) computes the normal range, (2) determines whether the testing procedure was stable and (3) transforms the test measurement scale to one based on the normal range, i.e., "normal quotient units."

The program was tested on 650 consecutive cases of patients with suspected thyroid disease, referred to the Department of Radiology of the University of Florida College of Medicine, on whom follow-up information of at least 6 months was available. The validity of the computed normal range of 24 hour I131 uptakes was established by examining the distribution of euthyroid patients after their status had been determined clinically.


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