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1 From the Department of Radiology, Division of Radiation Therapy, University of Miami School of Medicine, Miami, Florida
Two patients in late stages of pregnancy, who were affected by invasive carcinoma of the cervix and were treated in the immediate postpartum period by intracavitary cobalt 60 sources to a dose which resulted in permanent control of the tumors and who subsequently became pregnant are reported.
One of the patients delivered an infant who has remained apparently normal up to the age of 4
years when he was last seen.
A brief review of 11 similar cases from the literature is presented. It is concluded that the position of the ovaries immediately postpartum often results in a relatively low dose of radiation to the ovaries, and the ovarian function is resumed after variable intervals of dysfunction. All but 1 of these cases were treated by some form of intracavitary application.
A follow-up study in 7 of 13 infants born to these mothers, ranging from 2 to 7 years, showed no gross abnormalities in health and development.
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