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Imaging Features of Posttransplantation Lymphoproliferative Disorder in Pancreas Transplant Recipients

Toni L. Meador1,2, Thorsten L. Krebs1,3, Jade J. Wong You Cheong1, Barry Daly1, Susan Keay4 and Stephen Bartlett5

1 Department of Radiology, University of Maryland School of Medicine, 22 S. Green St., Baltimore, MD 21205.
4 Department of Infectious Disease, University of Maryland School of Medicine, Baltimore, MD 21205.
5 Department of Surgery, University of Maryland School of Medicine, Baltimore, MD 21205.



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  		Fig. 1 —54-year-old man with suspected acute rejection of pancreas and kidney allografts.

A, Transverse sonogram shows heterogeneous mass (arrowheads) in head of pancreas allograft. Percutaneous biopsy revealed combined B-cell hyperplasia and B-cell lymphoma.

 


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  		Fig. 1 —54-year-old man with suspected acute rejection of pancreas and kidney allografts.

B, Corresponding contrast-enhanced CT scan shows poorly marginated low-attenuation mass (arrow) in head of pancreas allograft. Note normally enhancing renal allograft.

 


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  		Fig. 1 —54-year-old man with suspected acute rejection of pancreas and kidney allografts.

C, Fast spin-echo fat-suppressed T2-weighted axial MR image (TR/TE, 5161/102) shows low-signal-intensity mass (arrowheads) within pancreas allograft. Mass corresponds to that seen in B.

 


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  		Fig. 2. —38-year-old man with decreased urine output 14 days after transplantation.

A, Unenhanced CT scan shows closely apposed diffusely enlarged pancreas (open arrows) and kidney (solid arrow) allografts. Note ascites. Surgical biopsy revealed polyclonal B-cell hyperplasia in pancreas and kidney allografts and in gallbladder.

 


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  		Fig. 2. —38-year-old man with decreased urine output 14 days after transplantation.

B, Fast spin-echo fat-suppressed T2-weighted axial MR image (TR/TE, 6372/102) shows enlarged pancreas (open arrows) and kidney (solid arrow) allografts with normal homogeneous signal intensity. Note duodenal cuff (arrowhead).

 

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