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Core Needle Breast Biopsy in Patients Undergoing Anticoagulation Therapy

Preliminary Results

Michelle K. Melotti1 and Wendie A. Berg1,2

1 Department of Diagnostic Radiology, University of Maryland School of Medicine, 22 S. Greene St., Baltimore, MD 21201.
2 Greenebaum Cancer Center, University of Maryland, Baltimore, MD 21201.



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Fig. 1. —68-year-old woman undergoing warfarin therapy for atrial fibrillation with two malignant palpable masses in right breast.

A and B, Craniocaudal (A) and mediolateral oblique (B) mammograms show spiculated mass (arrow) with associated calcifications, skin retraction, and skin thickening at 8-o'clock position in right breast, highly suspicious for cancer. Note second lobulated mass more superiorly at 10-o'clock position, which was indeterminate for malignancy.

 


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Fig. 1. —68-year-old woman undergoing warfarin therapy for atrial fibrillation with two malignant palpable masses in right breast.

A and B, Craniocaudal (A) and mediolateral oblique (B) mammograms show spiculated mass (arrow) with associated calcifications, skin retraction, and skin thickening at 8-o'clock position in right breast, highly suspicious for cancer. Note second lobulated mass more superiorly at 10-o'clock position, which was indeterminate for malignancy.

 


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Fig. 1. —68-year-old woman undergoing warfarin therapy for atrial fibrillation with two malignant palpable masses in right breast.

C, Sonogram shows spiculated mass seen in A and B. Initial 14-gauge core needle biopsy revealed infiltrating ductal carcinoma, which was confirmed at excision.

 


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Fig. 1. —68-year-old woman undergoing warfarin therapy for atrial fibrillation with two malignant palpable masses in right breast.

D, Sonogram shows lobulated mass (cursors) seen in A and B. Infiltrating and intraductal carcinoma were documented by both 14-gauge core needle breast biopsy and mastectomy. No bleeding or hematoma occurred at initial biopsy performed while patient continued anticoagulation therapy. No hematoma occurred at mastectomy 6 weeks later.

 


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Fig. 2. —Similar rates of hematoma formation were noted in patients biopsied with and without concurrent anticoagulation therapy.

A, 17-mm hematoma (arrow) documented on digital spot mammographic imaging after 11-gauge stereotactic biopsy in patient undergoing anticoagulation therapy with warfarin. Minimal air is seen within hematoma.

 


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Fig. 2. —Similar rates of hematoma formation were noted in patients biopsied with and without concurrent anticoagulation therapy.

B, Digital spot mammogram shows 12-mm hematoma and minimal air (arrowheads) after 11-gauge stereotactic biopsy in patient not known to be anticoagulated. Both biopsies yielded fibrocystic changes with microcalcifications.

 

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