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Development of a Digital Image Database for Chest Radiographs With and Without a Lung Nodule

Receiver Operating Characteristic Analysis of Radiologists' Detection of Pulmonary Nodules

Junji Shiraishi1, Shigehiko Katsuragawa2, Junpei Ikezoe3, Tsuneo Matsumoto4, Takeshi Kobayashi5, Ken-ichi Komatsu6, Mitate Matsui7, Hiroshi Fujita8, Yoshie Kodera9 and Kunio Doi10

1 Department of Radiology, Osaka City University Hospital, 1-5-7 Asahi-machi, Abeno-ku, Osaka, Osaka 545-8586 Japan.
2 Department of Radiology, Iwate Medical University, 19-1 Uchimaru, Morioka, Iwate 020-8505 Japan.
3 Department of Radiology, Ehime University, Shizukawa, Shigenobu-cho, Onsen-gun, Ehime 791-0295 Japan.
4 Department of Radiology, Yamaguchi University, 1144 Ogushi, Ube, Yamaguchi 755-8506 Japan.
5 Department of Radiology, Kanazawa University, 5-11-80, Kotateno, Kanazawa, Ishikawa 920-0942 Japan.
6 Medical Engineering Division, Toshiba, 1-1-1 Shibaura, Minato-ku, Tokyo 105-8001 Japan.
7 Medical Imaging Division, Konica, 1 Sakura-cho, Hino, Tokyo 191-8511 Japan.
8 Department of Information Science, Faculty of Engineering, Gifu University, 1-1, Yanagido, Gifu, Gifu 501-1193 Japan.
9 Department of Radiological Technology, Nagoya University School of Health Sciences, 1-1-20 Taikouminami, Higashi-ku, Nagoya, Aichi 461-8673 Japan.
10 Kurt Rossmann Laboratories for Radiologic Image Research, Department of Radiology, The University of Chicago, 5841 S. Maryland Ave., MC2026, Chicago, IL 60637.



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  		Fig. 1. —Receiver operating characteristic curves for all observers in detecting lung nodules on laser-printed films. Note large variation in radiologists' detection of nodules.

 


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  		Fig. 2. —Comparison of average receiver operating characteristic curves from four institutions. Note that four curves were similar.

 


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  		Fig. 3. —Receiver operating characteristic curves for five groups of cases with different degrees of subtlety. Note that they were clearly distinguished as five curves, corresponding to their degrees of subtlety.

 


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  		Fig. 4. —Relationship between degree of subtlety and average confidence rating score used by observers in receiver operating characteristic experiment for presence of nodule. High correlation coefficient, r = 0.999, was obtained.

 


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  		Fig. 5. —Receiver operating characteristic curves obtained by use of three groups of cases with different degrees of subtlety. Note that these subsets can be used for testing various techniques and methods.

 

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