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Interscan Variation in Coronary Artery Calcium Quantification in a Large Asymptomatic Patient Population

Hyo-Chun Yoon1, Jonathan G. Goldin2, Lloyd E. Greaser, III2, James Sayre3 and Gregg C. Fonarow4

1 Department of Radiology, 1A71 School of Medicine, University of Utah School of Medicine, 50 N. Medical Dr., Salt Lake City, UT 84132.
2 Department of Radiological Sciences, B2-247 CHS, UCLA School of Medicine, 10833 Le Conte Ave., Los Angeles, CA 90095.
3 Department of Radiological Sciences and Biomathematics, B2-200 CHS, UCLA School of Medicine, Los Angeles, CA 90095.
4 Department of Cardiology, UCLA School of Medicine, Los Angeles, CA 90095.



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  		Fig. 1. —Scatterplot shows comparison of log10 (calcium score + 1) transformed values from scan 1 versus scan 2. Note excellent overall correlation between two scans over entire range of calcium scores (R2 = 0.97).

 


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  		Fig. 2. —Bland-Altman plot shows comparison of percentage of difference in calcium scores versus mean values of calcium scores. Large percentage differences are seen mainly in patients with low calcium scores, but a few patients with scores greater than 500 had percentage differences exceeding 50%.

 

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