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Comparative Value of 99mTc-Sestamibi Scintimammography and Sonography in the Diagnostic Workup of Breast Masses

Anita J. Klaus1,2, William C. Klingensmith, III1, Steve H. Parker1, A. Thomas Stavros1, Jerome D. Sutherland1 and Kathy D. Aldrete1

1 Radiology Imaging Associates and The Sally Jobe Breast Center, 8200 E. Belleview Ave., Englewood, CO 80111.
2 Present Address: Wellspring Breast Center, Physicians Building South, Community General Hospital, 4000 Broad Rd., Syracuse, NY 13215.



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  		Fig. 1A. —True-positive sonographic findings and true-positive scintimammographic findings in 49-year-old woman with palpable lump in right breast. Mammograms show spiculated lesion (arrows) in inferior right breast.

 


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  		Fig. 1B. —True-positive sonographic findings and true-positive scintimammographic findings in 49-year-old woman with palpable lump in right breast. Mammograms show spiculated lesion (arrows) in inferior right breast.

 


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  		Fig. 1C. —True-positive sonographic findings and true-positive scintimammographic findings in 49-year-old woman with palpable lump in right breast. Sonogram shows suspicious hypoechoic mass (cursors).

 


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  		Fig. 1D. —True-positive sonographic findings and true-positive scintimammographic findings in 49-year-old woman with palpable lump in right breast. 99mTc-sestamibi scintimammograms show corresponding grade II uptake (solid arrow, D) with bilateral axillary node uptake (open arrows, D and E). Diagnosis was grade I infiltrating duct carcinoma with negative nodes.

 


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  		Fig. 1E. —True-positive sonographic findings and true-positive scintimammographic findings in 49-year-old woman with palpable lump in right breast. 99mTc-sestamibi scintimammograms show corresponding grade II uptake (solid arrow, D) with bilateral axillary node uptake (open arrows, D and E). Diagnosis was grade I infiltrating duct carcinoma with negative nodes.

 


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  		Fig. 2A. —True-positive sonographic findings and false-negative scintimammographic findings in 56-year-old woman with asymmetry on screening mammography. Sonogram shows hypoechoic shadowing mass in 10-o'clock position of right breast.

 


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  		Fig. 2B. —True-positive sonographic findings and false-negative scintimammographic findings in 56-year-old woman with asymmetry on screening mammography. 99mTc-sestamibi scintimammograms show no uptake in area of lesion, but do show uptake in axillary nodes bilaterally (arrows). Diagnosis was grade I infiltrating duct carcinoma with negative nodes.

 


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  		Fig. 2C. —True-positive sonographic findings and false-negative scintimammographic findings in 56-year-old woman with asymmetry on screening mammography. 99mTc-sestamibi scintimammograms show no uptake in area of lesion, but do show uptake in axillary nodes bilaterally (arrows). Diagnosis was grade I infiltrating duct carcinoma with negative nodes.

 


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  		Fig. 3A. —False-positive sonographic findings and true-negative scintimammographic findings in 64-year-old woman with palpable lump in left lateral breast. Sonogram shows suspicious hypoechoic lesion.

 


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  		Fig. 3B. —False-positive sonographic findings and true-negative scintimammographic findings in 64-year-old woman with palpable lump in left lateral breast. Scintimammogram reveals normal findings. Diagnosis was fibrocystic change and papilloma.

 

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