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Early Rethrombosis of Clotted Hemodialysis Grafts

Graft Salvage Achieved with an Aggressive Approach

Sean P. Murray1,2, Thomas B. Kinney1, Karim Valji1, Anne C. Roberts1, Steven C. Rose1 and Steven B. Oglevie1

1 Department of Radiology, University of California—San Diego, 200 W. Arbor Dr., San Diego, CA 92103.
2 Present address: Department of Radiology, Kaweah Delta Hospital, 400 W. Mineral King, Visalia, CA 93291-6263.



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Fig. 1. —Graph shows life table analysis of patency rates after technically successful pharmacomechanical thrombolysis of 39 clotted hemodialysis grafts. Note that survival rates improve markedly after 3 months, reflecting long-term benefit of aggressive approach. Time to repeated intervention (primary treatment) = [UNK], time to failure or revision (secondary treatment) = [UNK].

 


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Fig. 2. —Graph shows life table analysis of 39 "failed" grafts after pharmacomechanical thrombolysis compared with primary patency of various mechanical and pharmacomechanical studies. Note that our patency rate ([UNK]) compares reasonably with those obtained using other methods. Valji et al. [3] = [UNK], Trerotola et al. [5] = [UNK], Sharafuddin et al. [6] = {Delta}, Beathard et al. [7] = x, Trerotola et al. [8] = {diamondsuit}.

 


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Fig. 3. —Graph shows life table analysis comparing secondary patency after pharmacomechanical thrombolysis of 39 "failed" grafts from our study ([UNK]) with overall institutional hemodialysis graft secondary patency of 81 "failed" grafts from the study of Valji et al. [3] ([UNK]). Although no significant difference between these survival curves exists, a trend toward late divergence of results is noted (Kaplan-Meier product-limit difference, p = 0.76).

 

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