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Comparison of Rate of Development and Rate of Change for Benign and Malignant Breast Calcifications at the Lumpectomy Bed

Catherine S. Giess1,2,3, Delia M. Keating1, Michael P. Osborne4, Jolinda Mester1 and Ruth Rosenblatt1

1 Department of Radiology, The New York Presbyterian Hospital, Strang-Cornell Breast Center, 525 E. 68th St., New York, NY 10021.
2 Present address: Women's Diagnostic and Wellness Center, Nyack Hospital, 160 N. Midland Ave., Nyack, NY 10960.
3 Present address: Hudson Valley Radiology Associates, PLLC, 18 Squadron Blvd., New City, NY 10956.
4 Department of Surgery, The New York Presbyterian Hospital, Strang-Cornell Breast Center, New York, NY 10021.



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  		Fig. 1A. —49-year-old woman who developed two new smooth linear calcifications at lumpectomy bed 54 months after lumpectomy. Craniocaudal mammogram shows calcifications (arrowhead) interpreted as probably benign.

 


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  		Fig. 1B. —49-year-old woman who developed two new smooth linear calcifications at lumpectomy bed 54 months after lumpectomy. Craniocaudal mammogram obtained 6 months later shows calcifications (arrowhead) to be more coarse and coalescent than on A, consistent with sutural calcifications.

 


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  		Fig. 2A. —81-year-old woman who developed faint mildly pleomorphic calcifications 15 months after lumpectomy. Spot magnification craniocaudal mammogram shows six to 10 faint calcifications (arrowheads). These could not be localized on the magnified mediolateral oblique mammogram despite additional imaging.

 


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  		Fig. 2B. —81-year-old woman who developed faint mildly pleomorphic calcifications 15 months after lumpectomy. At 6-month follow-up, calcifications had increased in number and pleomorphism and were evident on spot magnification mediolateral mammogram (arrowhead) and on follow-up craniocaudal image (not shown). Biopsy yielded recurrent invasive and in situ ductal carcinoma.

 


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  		Fig. 3. —56-year-old woman who developed clustered pleomorphic calcifications at lumpectomy bed 54 months after lumpectomy. Calcifications are shown (arrowhead) on spot magnification craniocaudal mammogram. Biopsy yielded recurrent ductal carcinoma in situ.

 

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